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Blood levels of histone-complexed DNA fragments are associated with coagulopathy, inflammation and endothelial damage early after trauma

BACKGROUND: Tissue injury increases blood levels of extracellular histones and nucleic acids, and these may influence hemostasis, promote inflammation and damage the endothelium. Trauma-induced coagulopathy (TIC) may result from an endogenous response to the injury that involves the neurohumoral, in...

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Detalles Bibliográficos
Autores principales:	Johansson, Pär I, Windeløv, Nis A, Rasmussen, Lars S, Sørensen, Anne Marie, Ostrowski, Sisse R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746437/ https://www.ncbi.nlm.nih.gov/pubmed/23960372 http://dx.doi.org/10.4103/0974-2700.115327

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