Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach

It is well established that transcriptional silencing of critical tumor-suppressor genes by DNA methylation is a fundamental component in the initiation of breast cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in breast cancer is not well unders...

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Detalles Bibliográficos
Autores principales: Starlard-Davenport, Athena, Kutanzi, Kristi, Tryndyak, Volodymyr, Word, Beverly, Lyn-Cook, Beverly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746452/
https://www.ncbi.nlm.nih.gov/pubmed/23961262
http://dx.doi.org/10.4103/1477-3163.115720

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746452/
https://www.ncbi.nlm.nih.gov/pubmed/23961262
http://dx.doi.org/10.4103/1477-3163.115720

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