Cargando…

Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach

It is well established that transcriptional silencing of critical tumor-suppressor genes by DNA methylation is a fundamental component in the initiation of breast cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in breast cancer is not well unders...

Descripción completa

Detalles Bibliográficos
Autores principales: Starlard-Davenport, Athena, Kutanzi, Kristi, Tryndyak, Volodymyr, Word, Beverly, Lyn-Cook, Beverly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746452/
https://www.ncbi.nlm.nih.gov/pubmed/23961262
http://dx.doi.org/10.4103/1477-3163.115720

Ejemplares similares