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Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach
It is well established that transcriptional silencing of critical tumor-suppressor genes by DNA methylation is a fundamental component in the initiation of breast cancer. However, the involvement of microRNAs (miRNAs) in restoring abnormal DNA methylation patterns in breast cancer is not well unders...
Autores principales: | Starlard-Davenport, Athena, Kutanzi, Kristi, Tryndyak, Volodymyr, Word, Beverly, Lyn-Cook, Beverly |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746452/ https://www.ncbi.nlm.nih.gov/pubmed/23961262 http://dx.doi.org/10.4103/1477-3163.115720 |
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