Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes

Inhalable glycol chitosan-coated poly(lactic-co-glycolic acid) (PLGA) nanoparticles containing palmitic acid-modified exendin-4 (Pal-Ex4) (chitosan Pal-Ex4 PLGA NPs) were prepared and characterized. The surface morphology, particle size, and zeta potential of chitosan Pal-Ex4 PLGA NPs were investiga...

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Detalles Bibliográficos
Autores principales: Lee, Changkyu, Choi, Ji Su, Kim, Insoo, Oh, Kyung Taek, Lee, Eun Seong, Park, Eun-Seok, Lee, Kang Choon, Youn, Yu Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746731/
https://www.ncbi.nlm.nih.gov/pubmed/23976850
http://dx.doi.org/10.2147/IJN.S48197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746731/
https://www.ncbi.nlm.nih.gov/pubmed/23976850
http://dx.doi.org/10.2147/IJN.S48197

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