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Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes
Inhalable glycol chitosan-coated poly(lactic-co-glycolic acid) (PLGA) nanoparticles containing palmitic acid-modified exendin-4 (Pal-Ex4) (chitosan Pal-Ex4 PLGA NPs) were prepared and characterized. The surface morphology, particle size, and zeta potential of chitosan Pal-Ex4 PLGA NPs were investiga...
Autores principales: | Lee, Changkyu, Choi, Ji Su, Kim, Insoo, Oh, Kyung Taek, Lee, Eun Seong, Park, Eun-Seok, Lee, Kang Choon, Youn, Yu Seok |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746731/ https://www.ncbi.nlm.nih.gov/pubmed/23976850 http://dx.doi.org/10.2147/IJN.S48197 |
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