Synthesis of novel tetravalent galactosylated DTPA-DSPE and study on hepatocyte-targeting efficiency in vitro and in vivo

For the purposes of obtaining a hepatocyte-selective drug delivery system, a novel tetravalent galactosylated diethylenetriaminepentaacetic acid-distearoyl phosphatidylethanolamine (4Gal-DTPA-DSPE) was synthesized. The chemical structure of 4Gal-DTPA-DSPE was confirmed by proton nuclear magnetic res...

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Detalles Bibliográficos
Autores principales: Xiao, Yan, Zhang, Huafang, Zhang, Zhaoguo, Yan, Mina, Lei, Ming, Zeng, Ke, Zhao, Chunshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746791/
https://www.ncbi.nlm.nih.gov/pubmed/23976853
http://dx.doi.org/10.2147/IJN.S47495

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746791/
https://www.ncbi.nlm.nih.gov/pubmed/23976853
http://dx.doi.org/10.2147/IJN.S47495

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