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Cardiac nuclear high mobility group box 1 prevents the development of cardiac hypertrophy and heart failure
AIMS: High mobility group box 1 (HMGB1) is an abundant and ubiquitous nuclear DNA-binding protein that has multiple functions dependent on its cellular location. HMGB1 binds to DNA, facilitating numerous nuclear functions including maintenance of genome stability, transcription, and repair. However,...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746952/ https://www.ncbi.nlm.nih.gov/pubmed/23708738 http://dx.doi.org/10.1093/cvr/cvt128 |