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SORLA-Mediated Trafficking of TrkB Enhances the Response of Neurons to BDNF

Stimulation of neurons with brain-derived neurotrophic factor (BDNF) results in robust induction of SORLA, an intracellular sorting receptor of the VPS10P domain receptor gene family. However, the relevance of SORLA for BDNF-induced neuronal responses has not previously been investigated. We now dem...

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Detalles Bibliográficos
Autores principales: Rohe, Michael, Hartl, Daniela, Fjorback, Anja Nawarecki, Klose, Joachim, Willnow, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747043/
https://www.ncbi.nlm.nih.gov/pubmed/23977241
http://dx.doi.org/10.1371/journal.pone.0072164