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Comparing Adjuvanted H28 and Modified Vaccinia Virus Ankara Expressing H28 in a Mouse and a Non-Human Primate Tuberculosis Model

Here we report for the first time on the immunogenicity and protective efficacy of a vaccine strategy involving the adjuvanted fusion protein “H28” (consisting of Ag85B-TB10.4-Rv2660c) and Modified Vaccinia Virus Ankara expressing H28. We show that a heterologous prime-boost regimen involving primin...

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Detalles Bibliográficos
Autores principales: Billeskov, Rolf, Christensen, Jan P., Aagaard, Claus, Andersen, Peter, Dietrich, Jes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747044/
https://www.ncbi.nlm.nih.gov/pubmed/23977248
http://dx.doi.org/10.1371/journal.pone.0072185