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Octarellin VI: Using Rosetta to Design a Putative Artificial (β/α)(8) Protein

The computational protein design protocol Rosetta has been applied successfully to a wide variety of protein engineering problems. Here the aim was to test its ability to design de novo a protein adopting the TIM-barrel fold, whose formation requires about twice as many residues as in the largest pr...

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Detalles Bibliográficos
Autores principales: Figueroa, Maximiliano, Oliveira, Nicolas, Lejeune, Annabelle, Kaufmann, Kristian W., Dorr, Brent M., Matagne, André, Martial, Joseph A., Meiler, Jens, Van de Weerdt, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747059/
https://www.ncbi.nlm.nih.gov/pubmed/23977165
http://dx.doi.org/10.1371/journal.pone.0071858