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Octarellin VI: Using Rosetta to Design a Putative Artificial (β/α)(8) Protein
The computational protein design protocol Rosetta has been applied successfully to a wide variety of protein engineering problems. Here the aim was to test its ability to design de novo a protein adopting the TIM-barrel fold, whose formation requires about twice as many residues as in the largest pr...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747059/ https://www.ncbi.nlm.nih.gov/pubmed/23977165 http://dx.doi.org/10.1371/journal.pone.0071858 |