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A Role for NF-κB Activity in Skin Hyperplasia and the Development of Keratoacanthomata in Mice

BACKGROUND: Previous studies have implicated NF-κB signaling in both cutaneous development and oncogenesis. However, these studies have been limited in part by the lethality that results from extreme over- or under-expression of NF-κB in available mouse models. Even cre-driven tissue specific expres...

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Detalles Bibliográficos
Autores principales: Poligone, Brian, Hayden, Matthew S., Chen, Luojing, Pentland, Alice P., Jimi, Eijiro, Ghosh, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747062/
https://www.ncbi.nlm.nih.gov/pubmed/23977171
http://dx.doi.org/10.1371/journal.pone.0071887