Differential Modulation of Functional Dynamics and Allosteric Interactions in the Hsp90-Cochaperone Complexes with p23 and Aha1: A Computational Study

Allosteric interactions of the molecular chaperone Hsp90 with a large cohort of cochaperones and client proteins allow for molecular communication and event coupling in signal transduction networks. The integration of cochaperones into the Hsp90 system is driven by the regulatory mechanisms that mod...

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Detalles Bibliográficos
Autores principales: Blacklock, Kristin, Verkhivker, Gennady M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747073/
https://www.ncbi.nlm.nih.gov/pubmed/23977182
http://dx.doi.org/10.1371/journal.pone.0071936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747073/
https://www.ncbi.nlm.nih.gov/pubmed/23977182
http://dx.doi.org/10.1371/journal.pone.0071936

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