Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses

Human dynamin-1-like protein (DNM1L) is a GTP-driven molecular machine that segregates mitochondria and peroxisomes. To obtain insights into its catalytic mechanism, we determined crystal structures of a construct comprising the GTPase domain and the bundle signaling element (BSE) in the nucleotide-...

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Detalles Bibliográficos
Autores principales: Wenger, Julia, Klinglmayr, Eva, Fröhlich, Chris, Eibl, Clarissa, Gimeno, Ana, Hessenberger, Manuel, Puehringer, Sandra, Daumke, Oliver, Goettig, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747075/
https://www.ncbi.nlm.nih.gov/pubmed/23977156
http://dx.doi.org/10.1371/journal.pone.0071835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747075/
https://www.ncbi.nlm.nih.gov/pubmed/23977156
http://dx.doi.org/10.1371/journal.pone.0071835

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