S100A8 and S100A9 Induce Cytokine Expression and Regulate the NLRP3 Inflammasome via ROS-Dependent Activation of NF-κB(1)

S100A8 and S100A9 are cytoplasmic proteins expressed by phagocytes. High concentrations of these proteins have been correlated with various inflammatory conditions, including autoimmune diseases such as rheumatoid arthritis and Crohn’s disease, as well as autoinflammatory diseases. In the present st...

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Detalles Bibliográficos
Autores principales: Simard, Jean-Christophe, Cesaro, Annabelle, Chapeton-Montes, Julie, Tardif, Mélanie, Antoine, Francis, Girard, Denis, Tessier, Philippe A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747084/
https://www.ncbi.nlm.nih.gov/pubmed/23977231
http://dx.doi.org/10.1371/journal.pone.0072138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747084/
https://www.ncbi.nlm.nih.gov/pubmed/23977231
http://dx.doi.org/10.1371/journal.pone.0072138

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