Amino Acids and mTOR Mediate Distinct Metabolic Checkpoints in Mammalian G1 Cell Cycle

OBJECTIVE: In multicellular organisms, cell division is regulated by growth factors (GFs). In the absence of GFs, cells exit the cell cycle at a site in G1 referred to as the restriction point (R) and enter a state of quiescence known as G0. Additionally, nutrient availability impacts on G1 cell cyc...

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Detalles Bibliográficos
Autores principales: Saqcena, Mahesh, Menon, Deepak, Patel, Deven, Mukhopadhyay, Suman, Chow, Victor, Foster, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747087/
https://www.ncbi.nlm.nih.gov/pubmed/23977397
http://dx.doi.org/10.1371/journal.pone.0074157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747087/
https://www.ncbi.nlm.nih.gov/pubmed/23977397
http://dx.doi.org/10.1371/journal.pone.0074157

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