Cargando…

A Reinforcing Circuit Action of Extrasynaptic GABA(A) Receptor Modulators on Cerebellar Granule Cell Inhibition

GABA(A) receptors (GABARs) are the targets of a wide variety of modulatory drugs which enhance chloride flux through GABAR ion channels. Certain GABAR modulators appear to acutely enhance the function of δ subunit-containing GABAR subtypes responsible for tonic forms of inhibition. Here we identify...

Descripción completa

Detalles Bibliográficos
Autores principales: Santhakumar, Vijayalakshmi, Meera, Pratap, Karakossian, Movses H., Otis, Thomas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747091/
https://www.ncbi.nlm.nih.gov/pubmed/23977374
http://dx.doi.org/10.1371/journal.pone.0072976