Disruption of microRNA Biogenesis Confers Resistance to ER Stress-Induced Cell Death Upstream of the Mitochondrion

Global downregulation of microRNAs (miRNAs) is a common feature of human tumors and has been shown to enhance cancer progression. Several components of the miRNA biogenesis machinery (XPO5, DICER and TRBP) have been shown to act as haploinsufficient tumor suppressors. How the deregulation of miRNA b...

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Detalles Bibliográficos
Autores principales: Cawley, Karen, Logue, Susan E., Gorman, Adrienne M., Zeng, Qingping, Patterson, John, Gupta, Sanjeev, Samali, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747093/
https://www.ncbi.nlm.nih.gov/pubmed/23977393
http://dx.doi.org/10.1371/journal.pone.0073870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747093/
https://www.ncbi.nlm.nih.gov/pubmed/23977393
http://dx.doi.org/10.1371/journal.pone.0073870

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