A Tumor-Penetrating Peptide Modification Enhances the Antitumor Activity of Thymosin Alpha 1

A serious limitation of numerous antitumor drugs is the incapacity to penetrate solid tumors. However, addition of an RGD fragment to peptide drugs might solve this problem. In this study, we explored whether the introduction of a permeability-enhancing sequence, such as iRGD (CRGDK/RGPD/EC) fragmen...

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Detalles Bibliográficos
Autores principales: Lao, Xingzhen, Liu, Meng, Chen, Jiao, Zheng, Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747120/
https://www.ncbi.nlm.nih.gov/pubmed/23977262
http://dx.doi.org/10.1371/journal.pone.0072242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747120/
https://www.ncbi.nlm.nih.gov/pubmed/23977262
http://dx.doi.org/10.1371/journal.pone.0072242

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