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Monoubiquitination and Activity of the Paracaspase MALT1 Requires Glutamate 549 in the Dimerization Interface

The mucosa-associated lymphoid tissue protein-1 (MALT1, also known as paracaspase) is a protease whose activity is essential for the activation of lymphocytes and the growth of cells derived from human diffuse large B-cell lymphomas of the activated B-cell subtype (ABC DLBCL). Crystallographic appro...

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Detalles Bibliográficos
Autores principales: Cabalzar, Katrin, Pelzer, Christiane, Wolf, Annette, Lenz, Georg, Iwaszkiewicz, Justyna, Zoete, Vincent, Hailfinger, Stephan, Thome, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747146/
https://www.ncbi.nlm.nih.gov/pubmed/23977204
http://dx.doi.org/10.1371/journal.pone.0072051