Regulatory Phosphorylation of Ikaros by Bruton's Tyrosine Kinase

Diminished Ikaros function has been implicated in the pathogenesis of acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Therefore, a stringent regulation of Ikaros is of paramount importance for normal lymphocyte ontogeny. Here we provide genetic and biochemical evidence...

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Detalles Bibliográficos
Autores principales: Ma, Hong, Qazi, Sanjive, Ozer, Zahide, Zhang, Jian, Ishkhanian, Rita, Uckun, Fatih M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747153/
https://www.ncbi.nlm.nih.gov/pubmed/23977012
http://dx.doi.org/10.1371/journal.pone.0071302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747153/
https://www.ncbi.nlm.nih.gov/pubmed/23977012
http://dx.doi.org/10.1371/journal.pone.0071302

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