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Ca(2+)/Calmodulin-Dependent Protein Kinase II Contributes to Hypoxic Ischemic Cell Death in Neonatal Hippocampal Slice Cultures

We have recently shown that p38MAP kinase (p38MAPK) stimulates ROS generation via the activation of NADPH oxidase during neonatal hypoxia-ischemia (HI) brain injury. However, how p38MAPK is activated during HI remains unresolved and was the focus of this study. Ca(2+)/calmodulin-dependent protein ki...

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Detalles Bibliográficos
Autores principales: Lu, Qing, Harris, Valerie A., Sun, Xutong, Hou, Yali, Black, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747161/
https://www.ncbi.nlm.nih.gov/pubmed/23976956
http://dx.doi.org/10.1371/journal.pone.0070750