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Genomic Grade Index (GGI): Feasibility in Routine Practice and Impact on Treatment Decisions in Early Breast Cancer

PURPOSE: Genomic Grade Index (GGI) is a 97-gene signature that improves histologic grade (HG) classification in invasive breast carcinoma. In this prospective study we sought to evaluate the feasibility of performing GGI in routine clinical practice and its impact on treatment recommendations. METHO...

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Detalles Bibliográficos
Autores principales: Metzger-Filho, Otto, Catteau, Aurélie, Michiels, Stefan, Buyse, Marc, Ignatiadis, Michail, Saini, Kamal S., de Azambuja, Evandro, Fasolo, Virginie, Naji, Sihem, Canon, Jean Luc, Delrée, Paul, Coibion, Michel, Cusumano, Pino, Jossa, Veronique, Kains, Jean Pierre, Larsimont, Denis, Richard, Vincent, Faverly, Daniel, Cornez, Nathalie, Vuylsteke, Peter, Vanderschueren, Brigitte, Peyro-Saint-Paul, Hélène, Piccart, Martine, Sotiriou, Christos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747186/
https://www.ncbi.nlm.nih.gov/pubmed/23990869
http://dx.doi.org/10.1371/journal.pone.0066848