Discovery of new Longin and Roadblock domains that form platforms for small GTPases in Ragulator and TRAPP-II

Guanine nucleotide exchange factors (GEFs) control the site and extent of GTPase activity. Longin domains (LDs) are found in many Rab-GEFs, including DENNs, MON1/CCZ1, BLOC-3 and the TRAPP complex. Other GEFs, including Ragulator, contain roadblock domains (RDs), the structure of which is closely re...

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Detalles Bibliográficos
Autores principales: Levine, Timothy P., Daniels, Rachel D., Wong, Louise H., Gatta, Alberto T., Gerondopoulos, Andreas, Barr, Francis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747258/
https://www.ncbi.nlm.nih.gov/pubmed/23511850
http://dx.doi.org/10.4161/sgtp.24262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747258/
https://www.ncbi.nlm.nih.gov/pubmed/23511850
http://dx.doi.org/10.4161/sgtp.24262

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