The Loss of Gnai2 and Gnai3 in B Cells Eliminates B Lymphocyte Compartments and Leads to a Hyper-IgM Like Syndrome

B lymphocytes are compartmentalized within lymphoid organs. The organization of these compartments depends upon signaling initiated by G-protein linked chemoattractant receptors. To address the importance of the G-proteins Gα(i2) and Gα(i3) in chemoattractant signaling we created mice lacking both p...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Il-Young, Park, Chung, Luong, Thuyvi, Harrison, Kathleen A., Birnbaumer, Lutz, Kehrl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747273/
https://www.ncbi.nlm.nih.gov/pubmed/23977324
http://dx.doi.org/10.1371/journal.pone.0072596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747273/
https://www.ncbi.nlm.nih.gov/pubmed/23977324
http://dx.doi.org/10.1371/journal.pone.0072596

Ejemplares similares