Cargando…

Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex

Amniote epiblast cells differentiate into mesoderm and endoderm lineages during gastrulation through a process called epithelial-to-mesenchymal transition (EMT). Molecular regulation of gastrulation EMT is poorly understood. Here we show that epiblast epithelial status was maintained by anchoring mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakaya, Yukiko, Sukowati, Erike W., Sheng, Guojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747297/
https://www.ncbi.nlm.nih.gov/pubmed/23940118
http://dx.doi.org/10.1083/jcb.201302075