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Epiblast integrity requires CLASP and Dystroglycan-mediated microtubule anchoring to the basal cortex
Amniote epiblast cells differentiate into mesoderm and endoderm lineages during gastrulation through a process called epithelial-to-mesenchymal transition (EMT). Molecular regulation of gastrulation EMT is poorly understood. Here we show that epiblast epithelial status was maintained by anchoring mi...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747297/ https://www.ncbi.nlm.nih.gov/pubmed/23940118 http://dx.doi.org/10.1083/jcb.201302075 |