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The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1

Although much is known about signaling factors downstream of Rho GTPases that contribute to epidermal differentiation, little is known about which upstream regulatory proteins (guanine nucleotide exchange factors [GEFs] or GTPase-activating proteins [GAPs]) are involved in coordinating Rho signaling...

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Detalles Bibliográficos
Autores principales: Dubash, Adi D., Koetsier, Jennifer L., Amargo, Evangeline V., Najor, Nicole A., Harmon, Robert M., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747303/
https://www.ncbi.nlm.nih.gov/pubmed/23940119
http://dx.doi.org/10.1083/jcb.201304133