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The GEF Bcr activates RhoA/MAL signaling to promote keratinocyte differentiation via desmoglein-1
Although much is known about signaling factors downstream of Rho GTPases that contribute to epidermal differentiation, little is known about which upstream regulatory proteins (guanine nucleotide exchange factors [GEFs] or GTPase-activating proteins [GAPs]) are involved in coordinating Rho signaling...
Autores principales: | Dubash, Adi D., Koetsier, Jennifer L., Amargo, Evangeline V., Najor, Nicole A., Harmon, Robert M., Green, Kathleen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747303/ https://www.ncbi.nlm.nih.gov/pubmed/23940119 http://dx.doi.org/10.1083/jcb.201304133 |
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