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hGAAP promotes cell adhesion and migration via the stimulation of store-operated Ca(2+) entry and calpain 2

Golgi antiapoptotic proteins (GAAPs) are highly conserved Golgi membrane proteins that inhibit apoptosis and promote Ca(2+) release from intracellular stores. Given the role of Ca(2+) in controlling cell adhesion and motility, we hypothesized that human GAAP (hGAAP) might influence these events. In...

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Detalles Bibliográficos
Autores principales: Saraiva, Nuno, Prole, David L., Carrara, Guia, Johnson, Benjamin F., Taylor, Colin W., Parsons, Maddy, Smith, Geoffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747308/
https://www.ncbi.nlm.nih.gov/pubmed/23940116
http://dx.doi.org/10.1083/jcb.201301016