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Design, synthesis, molecular modeling, and biological evaluation of sulfanilamide-imines derivatives as potential anticancer agents

A series of sulfanilamide Schiff base derivatives (1 to 15) have been designed as potential antitubulin agents depending on the chemical structures of combretastatine A-4 and isoquinoline sulfamate (antimitotic agents under investigation). The designed compounds were synthesized by microwave chemica...

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Detalles Bibliográficos
Autores principales: Mohamed, Sofian S., Tamer, Abdalkarem R., Bensaber, Salah M., Jaeda, Mousa I., Ermeli, Nouri B., Allafi, Aemen Ali, Mrema, Ibrahim A., Erhuma, Mabrouk, Hermann, Anton, Gbaj, Abdul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747319/
https://www.ncbi.nlm.nih.gov/pubmed/23708566
http://dx.doi.org/10.1007/s00210-013-0883-y