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CYP3A5∗3 and C3435T MDR1 Polymorphisms in Prognostication of Drug-Resistant Epilepsy in Children and Adolescents

Drug-resistant epilepsies still remain one of the most profound problems of contemporary epileptology. Several mechanisms of drug resistance are possible; among them, genetic factors have a prominent place. Much importance is attached to genes, which encode enzymes that metabolize antiepileptic drug...

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Detalles Bibliográficos
Autores principales: Emich-Widera, Ewa, Likus, Wirginia, Kazek, Beata, Niemiec, Paweł, Balcerzyk, Anna, Sieroń, Aleksander L., Żak, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747339/
https://www.ncbi.nlm.nih.gov/pubmed/23984379
http://dx.doi.org/10.1155/2013/526837