Effect of Folic Acid and Vitamin B(12) on Pemetrexed Antifolate Chemotherapy in Nutrient Lung Cancer Cells

Pemetrexed (MTA) is a multitargeted antifolate drug approved for lung cancer therapy. Clinically, supplementation with high doses of folic acid (FA) and vitamin B(12) (VB12) lowers MTA cytotoxicities. An antagonistic effect of FA/VB12 on MTA efficacy has been proposed. However, patients who receive...

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Detalles Bibliográficos
Autores principales: Yang, Tsung-Ying, Chang, Gee-Chen, Hsu, Shih-Lan, Huang, Yi-Rou, Chiu, Ling-Yen, Sheu, Gwo-Tarng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747471/
https://www.ncbi.nlm.nih.gov/pubmed/23984356
http://dx.doi.org/10.1155/2013/389046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747471/
https://www.ncbi.nlm.nih.gov/pubmed/23984356
http://dx.doi.org/10.1155/2013/389046

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