Ribophorin II regulates breast tumor initiation and metastasis through the functional suppression of GSK3β

Mutant p53 (mtp53) gain of function (GOF) contributes to various aspects of tumor progression including cancer stem cell (CSC) property acquisition. A key factor of GOF is stabilization and accumulation of mtp53. However, the precise molecular mechanism of the mtp53 oncogenic activity remains unclea...

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Detalles Bibliográficos
Autores principales: Takahashi, Ryou-u, Takeshita, Fumitaka, Honma, Kimi, Ono, Masaya, Kato, Kikuya, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747512/
https://www.ncbi.nlm.nih.gov/pubmed/23959174
http://dx.doi.org/10.1038/srep02474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747512/
https://www.ncbi.nlm.nih.gov/pubmed/23959174
http://dx.doi.org/10.1038/srep02474

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