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Old Cryptococcus neoformans Cells Contribute to Virulence in Chronic Cryptococcosis

Does cell age matter in virulence? The emergence of persister cells during chronic infections is critical for persistence of infection, but little is known how this occurs. Here, we demonstrate for the first time that the replicative age of the fungal pathogen Cryptococcus neoformans contributes to...

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Detalles Bibliográficos
Autores principales: Bouklas, Tejas, Pechuan, Ximo, Goldman, David L., Edelman, Batya, Bergman, Aviv, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747583/
https://www.ncbi.nlm.nih.gov/pubmed/23943761
http://dx.doi.org/10.1128/mBio.00455-13