Selective κ Opioid Antagonists nor-BNI, GNTI and JDTic Have Low Affinities for Non-Opioid Receptors and Transporters

BACKGROUND: Nor-BNI, GNTI and JDTic induce selective κ opioid antagonism that is delayed and extremely prolonged, but some other effects are of rapid onset and brief duration. The transient effects of these compounds differ, suggesting that some of them may be mediated by other targets. RESULTS: In...

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Detalles Bibliográficos
Autores principales: Munro, Thomas A., Huang, Xi-Ping, Inglese, Carmela, Perrone, Maria Grazia, Van't Veer, Ashlee, Carroll, F. Ivy, Béguin, Cécile, Carlezon, William A., Colabufo, Nicola A., Cohen, Bruce M., Roth, Bryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747596/
https://www.ncbi.nlm.nih.gov/pubmed/23976952
http://dx.doi.org/10.1371/journal.pone.0070701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747596/
https://www.ncbi.nlm.nih.gov/pubmed/23976952
http://dx.doi.org/10.1371/journal.pone.0070701

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