Comparative Analysis of Context-Dependent Mutagenesis in Humans and Fruit Flies

In general, mutation frequencies are context-dependent: specific adjacent nucleotides may influence the probability to observe a specific type of mutation in a genome. Recently, several hypermutable motifs were identified in the human genome. Namely, there is an increased frequency of T>C mutatio...

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Detalles Bibliográficos
Autores principales: Medvedeva, Sofya A., Panchin, Alexander Y., Alexeevski, Andrey V., Spirin, Sergey A., Panchin, Yuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747623/
https://www.ncbi.nlm.nih.gov/pubmed/23984310
http://dx.doi.org/10.1155/2013/173616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747623/
https://www.ncbi.nlm.nih.gov/pubmed/23984310
http://dx.doi.org/10.1155/2013/173616

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