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The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice

The transcytosis of antigens across the follicle-associated epithelium (FAE) of Peyer's patches by microfold cells (M cells) is important for the induction of efficient immune responses to mucosal antigens. The mucosal immune response is compromised by ageing, but effects on M cells were unknow...

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Detalles Bibliográficos
Autores principales: Kobayashi, A, Donaldson, D S, Erridge, C, Kanaya, T, Williams, I R, Ohno, H, Mahajan, A, Mabbott, N A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747980/
https://www.ncbi.nlm.nih.gov/pubmed/23360902
http://dx.doi.org/10.1038/mi.2012.141