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Stable T-bet(+)GATA-3(+) Th1/Th2 Hybrid Cells Arise In Vivo, Can Develop Directly from Naive Precursors, and Limit Immunopathologic Inflammation

Differentiated T helper (Th) cell lineages are thought to emerge from alternative cell fate decisions. However, recent studies indicated that differentiated Th cells can adopt mixed phenotypes during secondary immunological challenges. Here we show that natural primary immune responses against paras...

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Detalles Bibliográficos
Autores principales: Peine, Michael, Rausch, Sebastian, Helmstetter, Caroline, Fröhlich, Anja, Hegazy, Ahmed N., Kühl, Anja A., Grevelding, Christoph G., Höfer, Thomas, Hartmann, Susanne, Löhning, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747991/
https://www.ncbi.nlm.nih.gov/pubmed/23976880
http://dx.doi.org/10.1371/journal.pbio.1001633