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The HILDA Complex Coordinates a Conditional Switch in the 3′-Untranslated Region of the VEGFA mRNA

Cell regulatory circuits integrate diverse, and sometimes conflicting, environmental cues to generate appropriate, condition-dependent responses. Here, we elucidate the components and mechanisms driving a protein-directed RNA switch in the 3′UTR of vascular endothelial growth factor (VEGF)-A. We des...

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Detalles Bibliográficos
Autores principales: Yao, Peng, Potdar, Alka A., Ray, Partho Sarothi, Eswarappa, Sandeepa M., Flagg, Andrew C., Willard, Belinda, Fox, Paul L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747992/
https://www.ncbi.nlm.nih.gov/pubmed/23976881
http://dx.doi.org/10.1371/journal.pbio.1001635