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Prevalence of PALB2 Mutations in Breast Cancer Patients in Multi-Ethnic Asian Population in Malaysia and Singapore

BACKGROUND: The partner and localizer of breast cancer 2 (PALB2) is responsible for facilitating BRCA2-mediated DNA repair by serving as a bridging molecule, acting as the physical and functional link between the breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) proteins. Truncating mutations in t...

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Detalles Bibliográficos
Autores principales: Phuah, Sze Yee, Lee, Sheau Yee, Kang, Peter, Kang, In Nee, Yoon, Sook-Yee, Thong, Meow Keong, Hartman, Mikael, Sng, Jen-Hwei, Yip, Cheng Har, Taib, Nur Aishah Mohd, Teo, Soo-Hwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748013/
https://www.ncbi.nlm.nih.gov/pubmed/23977390
http://dx.doi.org/10.1371/journal.pone.0073638