The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist

Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the controversy regarding the pharmacological action...

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Detalles Bibliográficos
Autores principales: Erickson, Catherine E., Gul, Rukhsana, Blessing, Christopher P., Nguyen, Jenny, Liu, Tammy, Pulakat, Lakshmi, Bastepe, Murat, Jackson, Edwin K., Andresen, Bradley T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748024/
https://www.ncbi.nlm.nih.gov/pubmed/23977191
http://dx.doi.org/10.1371/journal.pone.0071980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748024/
https://www.ncbi.nlm.nih.gov/pubmed/23977191
http://dx.doi.org/10.1371/journal.pone.0071980

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