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The Mini-Chromosome Maintenance (Mcm) Complexes Interact with DNA Polymerase α-Primase and Stimulate Its Ability to Synthesize RNA Primers

The Mini-chromosome maintenance (Mcm) proteins are essential as central components for the DNA unwinding machinery during eukaryotic DNA replication. DNA primase activity is required at the DNA replication fork to synthesize short RNA primers for DNA chain elongation on the lagging strand. Although...

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Detalles Bibliográficos
Autores principales: You, Zhiying, De Falco, Mariarosaria, Kamada, Katsuhiko, Pisani, Francesca M., Masai, Hisao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748026/
https://www.ncbi.nlm.nih.gov/pubmed/23977294
http://dx.doi.org/10.1371/journal.pone.0072408