Establishment of Mouse Model of MYH9 Disorders: Heterozygous R702C Mutation Provokes Macrothrombocytopenia with Leukocyte Inclusion Bodies, Renal Glomerulosclerosis and Hearing Disability

Nonmuscle myosin heavy chain IIA (NMMHCIIA) encoded by MYH9 is associated with autosomal dominantly inherited diseases called MYH9 disorders. MYH9 disorders are characterized by macrothrombocytopenia and very characteristic inclusion bodies in granulocytes. MYH9 disorders frequently cause nephritis,...

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Detalles Bibliográficos
Autores principales: Suzuki, Nobuaki, Kunishima, Shinji, Ikejiri, Makoto, Maruyama, Shoichi, Sone, Michihiko, Takagi, Akira, Ikawa, Masahito, Okabe, Masaru, Kojima, Tetsuhito, Saito, Hidehiko, Naoe, Tomoki, Matsushita, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748045/
https://www.ncbi.nlm.nih.gov/pubmed/23976996
http://dx.doi.org/10.1371/journal.pone.0071187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748045/
https://www.ncbi.nlm.nih.gov/pubmed/23976996
http://dx.doi.org/10.1371/journal.pone.0071187

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