Mutations in LMNA Modulate the Lamin A - Nesprin-2 Interaction and Cause LINC Complex Alterations

BACKGROUND: In eukaryotes the genetic material is enclosed by a continuous membrane system, the nuclear envelope (NE). Along the NE specific proteins assemble to form meshworks and mutations in these proteins have been described in a group of human diseases called laminopathies. Laminopathies includ...

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Detalles Bibliográficos
Autores principales: Yang, Liu, Munck, Martina, Swaminathan, Karthic, Kapinos, Larisa E., Noegel, Angelika A., Neumann, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748058/
https://www.ncbi.nlm.nih.gov/pubmed/23977161
http://dx.doi.org/10.1371/journal.pone.0071850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748058/
https://www.ncbi.nlm.nih.gov/pubmed/23977161
http://dx.doi.org/10.1371/journal.pone.0071850

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