Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice

BACKGROUND AND AIM: Human and animal studies have clearly established tumor necrosis factor (TNF)α as an important mediator of Crohn’s disease pathogenesis. However, whether systemic or only local TNFα overproduction is required for the development of chronic intestinal inflammation and Crohn’s dise...

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Detalles Bibliográficos
Autores principales: Bamias, Giorgos, Dahman, Mohamed I., Arseneau, Kristen O., Guanzon, Mitchell, Gruska, Dennis, Pizarro, Theresa T., Cominelli, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748077/
https://www.ncbi.nlm.nih.gov/pubmed/23977323
http://dx.doi.org/10.1371/journal.pone.0072594

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748077/
https://www.ncbi.nlm.nih.gov/pubmed/23977323
http://dx.doi.org/10.1371/journal.pone.0072594

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