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Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice
BACKGROUND AND AIM: Human and animal studies have clearly established tumor necrosis factor (TNF)α as an important mediator of Crohn’s disease pathogenesis. However, whether systemic or only local TNFα overproduction is required for the development of chronic intestinal inflammation and Crohn’s dise...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748077/ https://www.ncbi.nlm.nih.gov/pubmed/23977323 http://dx.doi.org/10.1371/journal.pone.0072594 |