Effects of KCNQ2 Gene Truncation on M-Type Kv7 Potassium Currents

The KCNQ2 gene product, Kv7.2, is a subunit of the M-channel, a low-threshold voltage-gated K(+) channel that regulates mammalian and human neuronal excitability. Spontaneous mutations one of the KCNQ2 genes cause disorders of neural excitability such as Benign Familial Neonatal Seizures. However th...

Descripción completa

Detalles Bibliográficos
Autores principales: Robbins, Jon, Passmore, Gayle M., Abogadie, Fe C., Reilly, Joanne M., Brown, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748097/
https://www.ncbi.nlm.nih.gov/pubmed/23977150
http://dx.doi.org/10.1371/journal.pone.0071809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748097/
https://www.ncbi.nlm.nih.gov/pubmed/23977150
http://dx.doi.org/10.1371/journal.pone.0071809

Ejemplares similares