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Effects of KCNQ2 Gene Truncation on M-Type Kv7 Potassium Currents
The KCNQ2 gene product, Kv7.2, is a subunit of the M-channel, a low-threshold voltage-gated K(+) channel that regulates mammalian and human neuronal excitability. Spontaneous mutations one of the KCNQ2 genes cause disorders of neural excitability such as Benign Familial Neonatal Seizures. However th...
Autores principales: | Robbins, Jon, Passmore, Gayle M., Abogadie, Fe C., Reilly, Joanne M., Brown, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748097/ https://www.ncbi.nlm.nih.gov/pubmed/23977150 http://dx.doi.org/10.1371/journal.pone.0071809 |
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