Notch Pathway Activation Contributes to Inhibition of C2C12 Myoblast Differentiation by Ethanol

The loss of muscle mass in alcoholic myopathy may reflect alcohol inhibition of myogenic cell differentiation into myotubes. Here, using a high content imaging system we show that ethanol inhibits C2C12 myoblast differentiation by reducing myogenic fusion, creating smaller and less complex myotubes...

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Detalles Bibliográficos
Autores principales: Arya, Michelle A., Tai, Albert K., Wooten, Eric C., Parkin, Christopher D., Kudryavtseva, Elena, Huggins, Gordon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748126/
https://www.ncbi.nlm.nih.gov/pubmed/23977095
http://dx.doi.org/10.1371/journal.pone.0071632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748126/
https://www.ncbi.nlm.nih.gov/pubmed/23977095
http://dx.doi.org/10.1371/journal.pone.0071632

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