Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function

Inflammatory Bowel Disease (IBD) is a chronic inflammatory condition thought to reflect a failure of the enteral immune system to adequately regulate itself. Inflammatory stress drives up-regulation of heat-shock proteins (HSP) including the pro-inflammatory chaperone, HSP90. This protein sequesters...

Descripción completa

Detalles Bibliográficos
Autores principales: Collins, Colm B., Aherne, Carol M., Yeckes, Alyson, Pound, Kayla, Eltzschig, Holger K., Jedlicka, Paul, de Zoeten, Edwin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748235/
https://www.ncbi.nlm.nih.gov/pubmed/23321985
http://dx.doi.org/10.1038/mi.2012.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748235/
https://www.ncbi.nlm.nih.gov/pubmed/23321985
http://dx.doi.org/10.1038/mi.2012.134

Ejemplares similares